Case Study

VE3 Enables High-Performance Cloud-Based Research Platform

Driving Innovation, Cost Efficiency, and Sustainability in Genomics Research

Introduction

VE3 partnered with a leading UK genomics research institution to build a high-performance cloud-based platform. This project addressed computational challenges, reduced costs, and enhanced collaboration across regions.

Challenges

Limited Computing Power

Their on-premises infrastructure was inadequate for handling the growing computational demands, leading to delays in data processing and research.

High Maintenance Costs

The cost of maintaining and upgrading their existing HPC cluster was escalating, diverting resources away from research activities.

Collaboration Barriers

The institution struggled with facilitating seamless collaboration among researchers across different regions, hindering real-time data sharing and analysis.

Solution & Architecture

High-Performance Computing (HPC)

  • Customizable Resources: We tailored compute power with flexible CPU, memory, and storage allocations, allowing the institution to match their specific data processing needs.
  • Elastic Scaling: Resources were scaled up or down to handle fluctuating workloads, ensuring both peak performance and cost efficiency during intensive genomic analysis.
  • Optimized Workflows: The platform integrated industry-standard bioinformatics tools and pipelines (WDL, Cromwell, Nextflow, Snakemake, Galaxy) to streamline data analysis and accelerate research.

Advanced Data Processing and Storage

  • Comprehensive File Support: The solution supported all major Next Generation Sequencing (NGS) file formats, such as BCL, FASTQ, BAM, VCF, and BED, ensuring compatibility and ease of use.
  • Scalable Storage Solutions: We provided secure, scalable storage using Amazon S3, Google Cloud Storage, and Azure Data Lake Storage, ensuring easy access to the institution’s growing datasets.
  • Efficient Data Management: Automated data ingestion, preprocessing, and analysis workflows enhanced productivity and ensured accurate results across the research lifecycle.

Managed Cloud Infrastructure

VE3 managed the setup and maintenance of the cloud environment, allowing researchers to focus on their work while we handled the technology.

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Consulting & Support

Our genomics experts provided 24/7 support and guidance, helping the institution scale resources and optimize workflows.

Data Security & Compliance

We ensured robust security measures in line with HIPAA, GDPR, and ISO, using AWS tools for strict access control and monitoring.

Results and Benefits

The application of our UCD expertise yielded significant benefits for the educational institution:

  • Enhanced Research Capabilities: The high-performance cloud-based HPC environment enabled faster processing of large genomic datasets, accelerating discoveries and supporting more complex studies.
  • Cost Savings: By leveraging our solutions, the institution reduced computing costs by 50%, allowing them to reinvest savings into further research initiatives.
  • Elastic Scalability: The platform’s flexible scaling handled fluctuating workloads efficiently, optimizing performance and cost during peak and off-peak periods.
  • Global Collaboration: Improved data integration tools enabled real-time collaboration across regions, speeding up insights and enhancing research outcomes.
  • Sustainability Gains: The cloud infrastructure reduced physical hardware needs, lowering energy consumption and aligning with the institution’s sustainability goals.
  • Data Security and Compliance: Robust security measures and compliance with HIPAA and GDPR ensured the protection and confidentiality of sensitive genomic data.

Conclusion

The collaboration between VE3 and the research institution transformed the way genomic research is conducted. By implementing a high-performance cloud-based platform, VE3 addressed the institution’s computational challenges and enabled long-term success. The new solution allowed the institution to scale its operations efficiently, enhance global collaboration, and significantly reduce costs. With flexible resources, advanced data processing tools, and a focus on sustainability, VE3 empowered the institution to accelerate research, improve outcomes, and align with their sustainability goals. This innovative platform positions the institution to continue driving advancements in genomics research.

Innovating Ideas. Delivering Results.

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